2 курс / Нормальная физиология / Учебное_пособие_по_физиологии_крови_Авдеева_Е_В_,_Репалова_Н_В_
.pdf54. FIND THE CORRECT ANSWER!
THE NORMAL PROTHROMBIN TIME ACCORDING TO ABRAMSON AND VAINSHTEIN IS ABOUT:
1.6-8 minutes
2.15-20 seconds
3.40 seconds
4.120 seconds
55. FIND THE CORRECT ANSWER!
FIBRINOGEN IS FORMED IN:
1.bone marrow
2.liver
3.kidneys
4.spleen
5.tonsils
OBLIGATORY TASKS
It is compulsory to carry out the tasks for self-preparation
1.Draw the general scheme of hemostasis.
2.Is Rh-conflict possible, if a mother has Rh «-» blood and her fetus Rh «+» blood? Explain your conclusion.
3.A person with blood group A (II) needs to be transfused 2l of blood. Is it possible to transfuse the blood of a universal donor О(1) to him or her? Explain your conclusion.
4.A recipient, who has a Rh «-» blood was given repeated transfusion of Rh «+» blood. Does hemolysis of the donor erythrocytes occur in these conditions? Explain your conclusion.
5.What is the definition of practical value Rh facilities for people(men and women)?
6.In some cases of blood transfusion is it necessary to consider the donor agglutinins and recipient agglutinogens? In which cases can it be ignored?
7.Why is a person with group I blood group a universal donor and the person with group IV blood group is a universal recipient?
8.Prepare for surgery. A patient has found the clotting time to be 8 minutes , he postponed the operation and began treatment. a. Why postpone the operation?
b.What medications to assign the patient to make it possible to give him the necessary surgery?
9.Whrite the scheme of fibrinolysis.
10.The cause of the patient is set low blood clotting, assigned to treatment with vitamin K. Explain why such treatment has been appointed?
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CROSSWORD
Across:
1. Blood proteolytic enzyme that causes the translation of fibrinogen in to fibrin 4. Non-protein portion of hemoglobin containing iron atom
6. Dynamic constancy of the internal environment
10. The abbreviated name of one of the most important hematological theory.
13.Professor of the University of Dorpat, who offered enzymatic theory of blood clotting.
16.Australian scientist XIX-XX BB., Nobel Prize winner who discovered blood group properties, RH
19.One of the tissues of the internal environments
20.Shift of the active reaction of blood to the alkaline side
21.Alkaline earth metal requiring coagulation factor
Down:
2.Protein hemoglobin.
3.Shift of the active reaction of blood to the acid side.
4.A painful condition that occurs when there is a lack of certain plasma coagulants.
5.Muscular hemoglobin.
7.Destruction of red blood cell membranes, accompanied by the release of hemoglobin from the past.
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8. Vasoconstrictive substance contained in platelets.
9.A type of granulocytes.
10.Seal, tightening blood clot.
11.A variety of blood cells.
12.Anti blood clotting factor.
14.XII plasma coagulator.
15.A component of the blood.
17.A blood clot formed in blood vessels.
18.Czech physician opened the 4th group of blood, the author of the nomenclature of blood groups.
RECOMMENDED LITERATURE
1.Guyton, A.C. Textbook of medical physiology / A.C. Guyton, J.E. Hall. – 11 th ed. - Philadelphia: Elsevier Saunder. – 2006. – Ch. 35, 36.
2.Ganong, W.F. Review of medical physiology / W.F. Ganong. – 22 th ed. - New York : Lange Medical Books / McGraw-Hill. - 2005. – Section VI, Ch. 27.
3.Lecture material.
4.Avdeyeva, E.V. Supplement for laboratory classes in normal physiology (for
students of medical, stomatological and pharmaceutical faculties) / E.V. Avdeyeva., L.I. Khokhlova. - Kursk, 2004. - P. 8-9.
5. Zavyalov, A.V. Methodical handbook in normal physiology. Tasks for selfcontrol: physiology of blood system, cardiovascular physiology / A.V. Zavyalov, E.V. Avdeyeva, L.I. Khokhlova. – Kursk, 2000.
SUPPLEMENTARY LITERATURE
1.Gutnik, K.B. Physiology for “lazy” students / K.B. Gutnik, V. Kobrin, D. Nash. –
M.: Логосфера, 2009. – 200 p.
2.Widmaier, E. Vander’s human physiology. The mechanisms of body function /
E.Widmaier, H. Raff, K. Strang. – Boston : Mc. Graw-Hill, Higher Education, 2008. – 770 p.
MAJOR LABORATORY CLASS
TOPIC MOTIVATION
This topic concludes the physiology of blood system. It helps in systematizing the knowledge you have acquired in the previous section. It also helps you learn its connections with other physiological systems of the organism and study some clinical aspects of the topic. For a successful completion of this topic it is important to review some of the important tems enumerated below.
QUESTIONS GUIDELINES ON BLOOD PHYSIOLOGY
1.Blood as a system. Functions of blood.
2.Composition of blood. Importance of plasma minerals and plasma proteins.
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3.Red blood cells, their production, regulation and destruction.
4.Calculation of red blood cells. Calculation of hemoglobin quantity in blood. Calculation of color index.
5.Genesis of the leukocytes. Life span of white blood cells.
6.General characteristics of leukocytes.
7.Leukogram and its medical importance.
8.Calculation of leukocytes.
9.Osmotic and oncotic pressure of blood. Factors which influence the osmotic and oncotic pressure of blood.
10.Determination of osmotic resistance of erythrocytes. Erythrocyte sedimentation rate.
11.Buffer systems of blood.
12.Different types of acidosis and alkalosis.
13.Physical and chemical characteristics of platelets.
14.Hemostasis, its stages and mechanisms.
15.Anticoagulation mechanisms.
16.Neuro-humoral regulation of blood clotting.
17.Blood coagulation tests.
18.Blood groups. ABO system.
19.Rh blood types. Rh conflict.
20.Methods for blood groups determination.
21.Main principles of blood transfusion.
22.Direct and reverse agglutination.
RECOMMENDED LITERATURE
1.Guyton, A.C. Textbook of medical physiology / A.C. Guyton, J.E. Hall. – 11 th ed. – Philadelphia : Elsevier Saunder. – 2006. – Ch. 30, 32-36.
2.Ganong, W.F. Review of medical physiology / W. F. Ganong. – 22 th ed. - New York : Lange Medical Books / McGraw-Hill. - 2005. – Section VI, Ch. 27.
3.Lecture material.
4.Avdeyeva, E.V. Supplement for laboratory classes in normal physiology (for
students of medical, stomatological and pharmaceutical faculties) / E.V. Avdeyeva., L.I. Khokhlova. - Kursk, 2004. - P. 6-9.
5. Zavyalov, A.V. Methodical handbook in normal physiology. Tasks for selfcontrol: physiology of blood system, cardiovascular physiology / A.V. Zavyalov, E.V. Avdeyeva, L.I. Khokhlova. – Kursk, 2000.
SUPPLEMENTARY LITERATURE
1.Gutnik, K.B. Physiology for “lazy” students / K.B. Gutnik, V. Kobrin, D. Nash.
– M. : Логосфера, 2009. – 200 p.
2.Widmaier, E. Vander’s human physiology. The mechanisms of body function / E. Widmaier, H. Raff, K. Strang. – Boston : Mc. Graw-Hill, Higher Education, 2008. – 770 p.
104
REFERENCES
1.Агаджанян, Н.А. Нормальная физиология : учеб. для студентов мед. вузов / Н.А. Агаджанян, В.М. Смирнов. - 3-е изд., испр. и доп. – М. : МИА, 2012.
– 576 c.
2.Камкин, А.Г. Атлас по физиологии : учеб. пособие для студентов учреждений высш. проф. образования, обучающихся по дисциплине «Физиология человека» по специальностям: «Лечебное дело», «Медико-профилактическое дело», «Стоматология», «Педиатрия», «Фармация», «Мед. биохимия», «Мед. биофизика», «Мед. кибернетика». - М. : ГЭОТАР-Медиа, 2010. - Т. 1. - 404 с.
3.Нормальная физиология: практикум: учеб. пособие для мед. вузов / под ред.
К.В. Судакова. – М. : МИА, 2008. – 231 с.
4.Нормальная физиология: учеб. для студентов мед. вузов по специальностям «Лечебное дело» и «Педиатрия» / под ред. В.М. Смирнова. – 4-е изд., перераб. и доп. - М. : Академия, 2012. – 480 с.
5.Нормальная физиология: Учебник. – М. : ГЭОТАР-Медиа, 2009. – 688 с.
6.Нормальная физиология: Учебник / Р.С. Орлов, А.Д. Ноздрачев – 2-е изд., исправл. и доп. – М.: ГЭОТАР-Медиа, 2010. – 832 с.
7. Физиология человека: учеб. для студентов мед. вузов / под ред. В.М. Покровского, Г.Ф. Коротько. – 2-е изд., перераб. и доп. – М. : Медицина,
2007. – 655 с.
8. Физиология человека : пер. с англ. : в 3 т. / под ред. Р. Шмидта, Г. |
Тевса. - |
||
3-е изд. - М. : Мир, 2005. – Т. 1. - 198 |
с. |
|
|
9. Физиология |
человека. Атлас |
динамических систем / К.В. |
Судаков, |
В.В. Андрианов, В.Е. Вагин, И.И. Киселев; под ред. К.В. Судакова. – М. : ГЭОТАР-Медиа, 2009. – 416 с.
10.Уард, Дж. Наглядная физиология: учеб. пособие для студентов учреждений высш. проф. образования, обучающихся по дисциплине «Физиология» по специальностям: 060101.65 «Лечебное дело», 060103.65 «Педиатрия», 060104.65 «Медико-профилактическое дело», 060105.65 «Стоматология», а также для системы последипломной подготовки в интернатуре и клинич. ординатуре / Дж. Уард, Р. Линден, Р. Кларк; под ред. О.С. Глазычева, Е.Г. Ионкиерй. – М. : ГЭОТАР-Медиа, 2010. – 132 с.
11.Avdeyeva, E.V. Supplement for laboratory classes in normal physiology (for students of medical, stomatological and pharmaceutical faculties) / E.V. Avdeyeva, L.I. Khokhlova – Kursk : KSMU, 2004. – 45 р.
12.Guyton, A.C. Textbook of medical physiology / A.C. Guyton, J.E. Hall. –
13th ed. – M. : Логосфера, 2015.
13.Ganong, W.F. Review of medical physiology / W.F. Ganong. – 22 th ed. - New York : Lange Medical Books / McGraw-Hill, 2005. – Section VI, Ch. 27.
14.Garbuzova V.Yu., Physiology of the blood: educational book / V.Yu. Garbuzova, L.А. Los, O.A. Obukhova – Sumy: PublisherSumSU. – 2010. – 165 p.
15.Guyton, A.C. Textbook of medical physiology / A.C. Guyton, J.E. Hall. – 12th ed. – Philadelphia : Elsevier Saunder, 2008.
105
16.Methodical recommendations for practical classes on normal physiology for students of medical faculty / comp. E.V. Avdeeva, O.M. Zotova – Kursk: KSMU, 2012. - Part 2.
17.Widmaier, E. Vander’s human physiology. The mechanisms of body function / E. Widmaier, H. Raff, K. Strang. – Boston : Mc. Graw-Hill, Higher Education, 2008.
– 770 p.
18.Zavyalov, A.V. Methodical handbook in normal physiology. Tasks for selfcontrol: physiology of blood system, cardiovascular physiology / A.V. Zavyalov, E.V. Avdeyeva, L.I. Khokhlova. – Kursk, 2000. - 53 p.
Электронное информационное обеспечение и интернет-ресурсы
1.Электронная библиотека медицинского вуза «Консультант студента» www.studmedlib.ru.
2.Student’s manual on normal physiology: for medical students. Part 1 (электронная) № гос. рег. 0321200439 - Курск, 2012. Е.В.Авдеева, О.М.Зотова, И.В.Михайлов.
3.http://www.medkursor.ru
4.http://ucheba-legko.ru
5.http://meduniver.com
6.http://doctorspb.ru
7.http://www.studfiles.ru
8.http://congress-media.com
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CONTENTS
1.Preface…………………………………………………...……………….. 5
2. |
Functions of blood. Red blood cells……………………………………… |
7 |
3. |
Physico-chemical properties of blood. Physiology of leukocytes………. |
32 |
4.Hemostasis and blood coagulation. Blood groups. Transfusion…………. 65
5.Major laboratory class……………………………………………………. 103
6.References………………………………………………………………… 105
7.Pages for your notes………………………………………………………. 108
107
PAGES FOR YOUR NOTES
108