Acute kidney injury and chronic kidney disease
1. The preferable method of assessing renal filtration function (glomerular filtration rate):
1. Rehberg test
2. MDRD
3. CKD-EPI
4. Cockcroft formula
2. Which of the following is a diagnostic criterion for CKD:
1.↓GFR < 90 ml/min/1,73 m2 within > 3 months
2.↓GFR < 60 ml/min/1,73 m2 within > 3 months
3.↓GFR < 90 ml/min/1,73 m2 within >1 months
4.↓GFR < 60 ml/min/1,73 m2 within>1 months
3. Normal range of GFR is as follows:
40 – 60 ml/min
80 – 120 ml/min
4. Which of the following is an indication for assessing albuminuria in patients with diabetes mellitus:
proteinuria >3.5 g/24 hours
proteinuria >1 g/24 hours
no proteinuria
5. AKI can be caused by:
Renal arteries thrombosis
Urinary tract obstruction
Chronic pyelonephritis
Cardiogenic shock
6. AKI is characterized with:
Decrease in urine gravity
GFR < 60 ml/min/1,73m2 within > 3 months
Increase in serum creatinine > 26,5 mcmol/l within 48 hours
Diuresis <0,3 ml/kg/h for >24 hours or anuria > 12 hours
7. Which of the following can be used for GFR assessment:
urea clearance
creatinine clearance
uric acid clearance
potassium clearance
sodium clearance
8. 75 – year old patient:
History: 4 months ago creatinine level was 400 mcmol/l, GFR – 12 ml/min/1,73m2
Blood chemistry: creatinine – 480 mcmol/l, GFR – 9 ml/min/1,73m2
24 hour proteinuria – 600 mg
Urinalysis: leucocytes – 0-2 per HPF, specific gravity is 1006
Ultrasound: decreased kidney size (70х40 mm), parenchema – 10 mm
What’s the presumptive diagnosis?
AKI
Renal amiloidosis
CKD
Nephrotic syndrome
9. 60-year old patient with preserved kidney function, diabetes mellitus type 2, urolithiasis complains of nausea, vomiting, dyspnea, decreased amount of urine. These symptoms appeared after excretory urography.
Blood chemistry: creatinine 109→500 mcmol/l, GFR 63→3ml/мин/1,73m2, potassium 6.5 mmol/l.
Ultrasound: normal kidney size.
What’s the presumptive diagnosis?
Acute nephritic syndrome
Nephrotic syndrome
AKI
CKD
Upper urinary tract infection
10. 55-year old patient with long history of chronic glomerulonephritis (latent course) complains of fatigue, nocturia, headache.
General assessment: pale skin, BP 170/110 mmHg
CBC: Hb – 103 g/l
Blood chemistry: creatinine – 200 ml/min/1,73m2, GFR 33 ml/min.
Urinalysis: leucocytes – 0-1 per HPF, specific gravity is 1005, erythrocytes 8-10 per HPF.
Ultrasound: decreased kidney size.
What’s the presumptive diagnosis?
Acute nephritic syndrome
Nephrotic syndrome
AKI
CKD
Lower urinary tract infection
Necessary investigations -?
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