Phosphorus-containing derivatives of indole and pyrole (review). (англ

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O2N		O2N		O2N
		P(OEt)3		MnO
				2
O2N	N	(EtO)2(O)P	N	(EtO)2(O)P	N
	H		H		H
		60			61

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	COOEt	R2PO	COOEt
	HO
			S
	Et2NPR2
	N Me		N Me
	H		H
			62
	R2PO		COOEt
			N Me
			H
			63

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CH2NMe3I			CH2P(O)(OR)2
HO	COOEt	HO	COOEt
	P(OR)3
N	Me		N Me	ROH
H			H
		OR	64
		P
	O	CH2	COOEt
		N	Me
		H
		65

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Br	O		OH
			Br
		HP(O)(OEt)2
			P(O)(OEt)2
	N O	EtONa	N O
	H		H
			66
		(EtO)2(O)P	OH
			P(O)(OEt)2
	P(OEt)3
	NiBr2		N O
			H
			67

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N		N
H		H
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H			H

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				CH2OH				CH2OH	CH2OP(OR)NMe2
				(Me2N)2POR				+
	N								N
								N
	H								H
	80a							Me2NPOR	81
								80
	2(Me2N)2POR							CH2OP(OR)NMe2		CH2OX
	80a
			2Me2NH					N	N
								Me2NPOR	Y
									83–85
								82

83 X = H, Y = Me2NP(O)(OR); 84 X = P(O)(OR)NMe2, Y = H;

85 X = Y = P(O)(OR)NMe2

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			RP(OR')2
	X	O		O		X
RP(OR')2
49a–c
		N			N
		R''		87	R''
		P(O)(OR')R
	X	O		OR'		X
87
EtOH		N			N
		R''		88	R''

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		R	OH
			P(O)RR'
		P(O)H
	49a	R'
		N	O

H

89a–d

89a–d a R = R'= OMe; b R = R' = OEt; c R = OH, R' = p-C6H4Me; d R = OH, R' = -naphthyl

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	OP(O)(OR)2		OH
(RO)2P(O)H
49a
RONa	N O	O	N
	H	90	H

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		OH
H(O)P(OR')	2	CHP(O)(OR')2
47a,b
	91	R

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R'	N	N CH(OH)P(O)(OR)2
		CH(OH)P(O)(OR)2
	H
	92	X
		93

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	2PPh3				PPh3
49a					+ O		PPh3
	CH2Cl2		N
					O
			H
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N(CH2)nC6H4R'

(O)P(OR)2

(RO)2P(O)H

NNa

(CH2)nC6H4R'

N

RONa

N

H

H

Na

(CH2)nC6H4R'

(O)P(OR)2

N

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C H R'

N

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H

N

96a–f

(O)P(OR)2

H

96

N

N

(CH2)nC6H4R'

H

97a–e

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CH(NR2')P(O)(OR'')2

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98a–e

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P(OR')R''

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		R2NP(OR')R''	H
	49		99
		(R2N)3P

P(NR2)2

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	OH		NR2	OH		OH
			P(O)(OR')2			P(O)(OR')2
			Me			Me
	N			N
	H			H
	101			102
		OR			OR
		P			P	S
	O		O	O		O
			P(O)(OR')2			P(O)(OR')2
			Me			Me
	N			N
	H			H
	103			104

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O	O	O
N(CH2)nOH	RPR'R''	S
	N(CH2)nOPR'R''	N(CH2)nOP(S)R'R''
	105a–d	106a–d

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	O			O
	N(CH2)nCl	P(OR)3		NCH2P(O)(OR)2
		n = 1
107a–c			108

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105b,d + RI	N(CH2)nOP(O)R'(OR)
	109a,b

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107b	EtOPRR'	NCH2CH2P(O)RR'

110a–c

110 a R = R' = NAlk2; b R = NAlk2, R' = Et; c R = NAlk2, R' = Ph

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										NC(O)(CH2)n P(O)(OEt)2
			P(OEt)3							113a–c
	NC(O)(CH2)n Cl
111a–c										O
										N
								115 P(O)(OEt)2
			111, 113 a n = 1, b n = 2, c n = 3
			O				O
				P(OEt)3		NCH2CH2P(O)(OEt)2
			NCH2CH2Cl
			O			O
112						114

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		(EtO)2P(O)
		O
	P(OEt)3	N
	111a	O
	O	116
	P(OR)3	P(O)(OR)2
	NCH2CH2Cl

O N O

O

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