1-s2.0-S1547527117312407-main

ACCEPTED MANUSCRIPT

392Figure 4. Effects of treatment (EffectivCRT during AF) on % V pacing (left panel), % effective CRT

393pacing (center panel) and mean heart rate (right panel). Light blue bars indicate control (CAFR). Dark

394blue bars indicate EffectivCRT During AF (eCRTAF). Error bars show standard deviation.

% V Pacing		% Effective CRT Pacing			Mean Heart Rate (bpm)
100		100	p < 0.001		100	p < 0.001
p < 0.001
90		90			90		T
80		80			80
70		70			70
60		60			60
83.2	90.0		80.8	87.8		77.0	79.5
50		50			50	CRIP
		Control	EffectivCRT During AF
395				MANUS
396
ACCEPTED

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ACCEPTED MANUSCRIPT

397Figure 5. Results sub-grouped by %Vp under control (%Vp – top panel, %eCRT – middle panel, mean

398HR – bottom panel). Light blue bars indicate control (CAFR). Dark blue bars indicate EffectivCRT

399During AF (eCRTAF). Error bars show standard deviation.

100

90

80

70

60

50

100

90

80

70

60

50

85

80

75

70

65

60

400

% V Pacing

p = NS

p < 0.01

p < 0.001

MANUS

97.4

97.0

89.5

92.0

69.9

84.8

%LVP>95

80≤%LVP≤95

%LVP<80

% Effective CRT Pacing

(N=21)

(N=9)

(N=24)

p = NS

p < 0.05

p < 0.001

ACCEPTED

96.4

95.7

88.3

90.5

65.4

81.2

%LVP>95

80≤%LVP≤95

%LVP<80

Mean Heart Rate (bpm)

(N=21)

(N=9)

(N=24)

p < 0.01

p = NS

p < 0.01

74.9

76.2

73.6

76.5

82.0

84.4

%LVP>95

80≤%LVP≤95

%LVP<80

(N=9)

(N=24)

(N=21)

Control

EffectivCRT During AF

CRIP	T

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