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Author
Kim Moscatello, Ph.D.
Professor of Microbiology and Immunology
Lake Erie College of Osteopathic Medicine
Erie, PA
Contributors
Thomas F. Lint, Ph.D.
Professor of Immunology and Microbiology
Rush Medical College
Chicago, IL
Christopher C. Keller, Ph.D.
AssociateProfessor of Microbiology and Immunology
Lake Erie College of Osteopathic Medicine
Erie, PA
Previous contributions by Mary Ruebush, Ph.D.
Contents
Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii
Section I: Immunology
Chapter 1: Overview of the Immune System . . . . . . . . . . . . . . . . . . . . . . . . . 3
Chapter 2: Cells of the Immune System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Chapter 3: The Selection of Lymphocytes. . . . . . . . . . . . . . . . . . . . . . . . . . . 23
Chapter 4: Lymphocyte Recirculation and Homing . . . . . . . . . . . . . .. . . . . 33
Chapter 5: The First Response to Antigen . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
Chapter 6: The Processing and Presentation of Antigen . . . . . . . . . . . . . . . 51
Chapter 7: The Generation of Humoral Effector Mechanisms. . . . . . . . . . . 67
Chapter 8: The Generation of Cell-Mediated Effector Mechanisms . . . . . . 89
Chapter 9: The Generation of Immunologic Memory . . . . . . . . . . . . . . . . 101
Chapter 10: Vaccination and lmmunotherapy.. . . . . . . . . . . . . . . . . . . . . . |
107 |
Chapter 11: Immunodeficiency Diseases. . ......................... |
117 |
Chapter 12: Acquired Immunodeficiency Syndrome . ................ |
131 |
Chapter 13: Diseases Caused by Immune Responses: |
|
Hypersensitivity and Autoimmunity .................... |
141 |
Chapter 14: Transplantation Immunology. . . . . . . . . . . . . . . . . . . . . . . . . . |
159 |
Chapter 15: Laboratory Techniques in Immunology . . . . . . . . . . . . . . . . .. |
171 |
Appendix I: CD Markers........................................ |
185 |
Appendix II: Cytokines. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
187 |
MEDICAL V
Appendix Ht Mhes\on Mo\ecu\es. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191
Appendix IV: Mechanisms of Resistance to Microbial Infections . . . . . . . 193
Section II: Microbiology
Chapter 1: General Microbiology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199
Chapter 2: Medically Important Bacteria. . . . . . . . . . . . . . . . . . . . . . . . . . . 209
Chapter 3: Microbial Genetics/Drug Resistance . . . . . . . . . . . . . . . . . . . . . 311
Chapter 4: Medically Important Viruses . . . . . . . . . . . . . . . . . . . . . . . . . . . 347
Chapter s: Medically Important Fungi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419
Chapter 6: Medical Parasitology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435
Chapter 7: Clinical Infectious Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 457
Chapter 8: Comparative Microbiology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 483
Chapter 9: Flow Charts/Clue Sheets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 499
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 515
Vi MEDICAL
Preface
These 7 volumes of Lecture Notes represent the most-likely-to-be-tested material on the current USMLE Step 1 exam. Please note that these are Lecture Notes, not review books. The Notes were designed to be accompanied by faculty lectures-live,on video, or on the web. Reading them without accessing the accompanying lectures is not an effective way to review for the USMLE.
To maximize the effectiveness of these Notes, annotate them as you listen to lectures. To facilitate this process, we've created wide, blank margins. While these margins are occasionally punctuated by faculty high-yield "margin notes;' they are, for the most part, left blank for your notations.
Many students find that previewing the Notes prior to the lecture is a very effective way to prepare for class. This allows you to anticipate the areas where you'll need to pay particular attention. It also affords you the opportunity to map out how the infor mation is going to be presented and what sort of study aids (charts, diagrams, etc.) you might want to add. This strategy works regardless of whether you're attending a live lecture or watching one on video or the web.
Finally, we want to hear what you think. What do you like about the Notes? What could be improved? Please share your feedback by e-mailing us at medfeedback@kaplan.com.
Thank you for joining Kaplan Medical, and best ofluck on your Step 1 exam!
Kaplan Medical
MEDICAL |
vii |
SECTION
Immunology
