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Fifty Cases in Dermatological

Medicine

Daniel Creamer

Department of Dermatology

King’s College Hospital

Denmark Hill

London SE5 9RS

Anthony du Vivier

Department of Dermatology

King’s College Hospital

Denmark Hill

London SE5 9RS

LONDON AND NEW YORK A MARTIN DUNITZ BOOK

© 2005 Taylor & Francis, an imprint of the Taylor & Francis Group

First published in the United Kingdom in 2005 by Taylor & Francis, an imprint of the Taylor & Francis Group, 2 Park Square, Milton Park, Abingdon, Oxon OX14 4RN

Tel.: +44 (0) 1235 828600 Fax.: +44 (0) 1235 829000 E-mail: info@dunitz.co.uk Website:http://www.dunitz.co.uk/

This edition published in the Taylor & Francis e-Library, 2005.

“To purchase your own copy of this or any of Taylor & Francis or Routledge’s collection of thousands of eBooks please go to http://www.ebookstore.tandf.co.uk/.”

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior permission of the publisher or in accordance with the provisions of the Copyright, Designs and Patents Act 1988 or under the terms of any licence permitting limited copying issued by the Copyright Licensing Agency, 90 Tottenham Court Road, London W1P 0LP. Although every effort has been made to ensure that all owners of copyright material have been acknowledged in this publication, we would be glad to acknowledge in subsequent reprints or editions any omissions brought to our attention.

A CIP record for this book is available from the British Library.

Library of Congress Cataloging-in-Publication Data

Data available on application

ISBN 0-203-49289-7 Master e-book ISBN

ISBN 0-203-59565-3 (Adobe eReader Format)

ISBN 1 84184 143 9 (Print Edition)

Distributed in North and South America by Taylor & Francis 2000 NW Corporate Blvd Boca Raton, FL 33431, USA

Within Continental USA Tel.: 800 272 7737; Fax.: 800 374 3401

Outside Continental USA Tel.: 561 994 0555; Fax.: 561 361 6018 E-mail: orders@crcpress.com Distributed in the rest of the world by Thomson Publishing Services Cheriton House North Way Andover, Hampshire SP10 5BE, UK Tel: +44 (0)1264 332424 E-mail: selesorder.tandf@thomsonpublishingservices.co.uk

Dedication

This book is dedicated to our wives, Katherine and Judith.

 

Contents

 

 

Dedication

iii

 

Preface

ix

 

Acknowledgements

x

 

Abbreviations

xi

Case 1

Haematemesis and warts

1

Case 2

J Yeh, A du Vivier

 

Annular lesions on the face of a neonate

9

Case 3

E Higgins

 

A warty plaque on the sole of the foot

15

Case 4

P Gruber, D Vollum, A du Vivier

 

Dystrophic nails and lethargy

21

Case 5

A du Vivier

 

Stretchy skin

28

Case 6

L Whittam

 

Chronic scaling of the scalp

34

Case 7

B Monk, A du Vivier

 

Generalized papular thickening of the skin

41

Case 8

A du Vivier

 

Flexural erythema following chemotherapy

48

Case 9

K Harman, E Higgins

 

Painful pustules in pregnancy

54

Case

E Higgins, A Pembroke

 

Discharging nodules on the jaw

60

10

J White, C Fuller

 

Case

Thickening of the facial skin, weakness of the hands and loss of

67

11peripheral sensation

M Clement, A du Vivier

Case

A facial and anogenital rash in an infant

74

12

M Clement

 

Case

Non-healing dog bites

80

13

E Higgins, A du Vivier

 

Case

Two patients with pustular plaques on a neurosurgical ward

87

14

S Munn, A du Vivier

 

Case

Fever and purpuric lesions in an infant

93

15

A du Vivier

 

Case

Photosensitivity with skin cancers

100

16

A Pembroke, A du Vivier

 

Case

A papular eruption in a patient with leukaemia

108

17

K Watson, A du Vivier

 

Case

A polycyclic rash in a patient with epilepsy

116

18

J White, D Creamer

 

Case

Flexural papules, thirst and polyuria

123

19

A Pembroke

 

Case

Facial plaques and fever

129

20

P Todd, A Pembroke

 

Case

Generalized thickening of the skin following bone marrow

136

21transplantation

G Osborne

Case

Pruritic plaques in pregnancy

143

22

A du Vivier

 

Case

Multiple painless ulcers in a traveller

150

23

B Monk

 

Case

A pigmented plaque on the knee

156

24

E Higgins

 

Case

Photosensitivity with scarring

162

25

S Dawe, DI Williams, D Creamer

 

Case

Swelling of the hands and generalized hyperpigmentation

169

26

A du Vivier

 

Case

Birthmarks and macrodactyly

176

27

F Child, A du Vivier

 

Case

Facial nodules, cough and breathlessness

183

28

A Pembroke

 

Case

A unilateral breast rash

189

29

E Campalani, A du Vivier

 

Case

Fever and a desquamating rash in an infant

196

30

E Higgins

 

Case

A follicular eruption in a vegan

202

31

C Martyn-Simmons, A du Vivier

 

Case

Erythroderma in a Jamaican man

208

32

G Osborne, A du Vivier

 

Case

An inflamed toe and a rash on the legs in an immunosuppressed patient

214

33

F Child, A du Vivier

 

Case

Periorbital erythema following chemotherapy

221

34

F Keane,A du Vivier

 

Case

Nodules and plaques in a boy with progressive liver failure

226

35

D Buckley, A du Vivier

 

Case

A unilateral groin rash

233

36

K Short, A du Vivier

 

Case

Patches, plaques and lymphadenopathy

239

37

M Clement, A du Vivier

 

Case

A plaque on the shin

245

38

M Clement

 

Case

A rash and numbness involving the right thumb

251

39

S Dawe, D Creamer

 

Case

Widespread skin sloughing in a man with fits

258

40

D Creamer

 

Case

A plaque on the chest

267

41

D Creamer

 

Case

A polymorphic mucocutaneous eruption in a patient with lymphoma

274

42

G Perera, D Creamer

 

Case

Abdominal pain, fever and acral purpura

284

43

A Friedmann, D Creamer

 

Case

Papules on the buttocks

291

44

A du Vivier

 

Case

A non-healing crusted plaque in a child

297

45

J White, E Higgins

 

Case

A rash on the face, upper back and hands

304

46

D Creamer, A du Vivier

 

Case

A large vascular tumour in an HIV-positive man

314

47

Kazim Aderogba, Karen Watson, Christopher Taylor

 

Case

Linear blisters and pigmentation in a baby girl

320

48

M Clement

 

Case

Gradual coarse wrinkling of the skin

326

49

A Friedmann, R Marten

 

Case

Breathlessness and widespread cutaneous necrosis

333

50

K Watson, D Creamer

 

 

Index

341

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