- •Part II reader хрестоматія
- •Guidelines for Safe and Effective Drug Use
- •Nitroglycerin
- •Inform Your Physician Before Taking This Drug If
- •Aspirin (as pir in)
- •Captopril
- •Inform Your Physician Before Taking This Drug If
- •Metronidazole
- •Inform Your Physician Before Taking This Drug If
- •Estrogens
- •Inform Your Physician Before Taking This Drug If
- •Dexamethasone
- •Inform Your Physician Before Taking This Drug If
- •If any of the following develop, consult your physician promptly for guidance.
- •Omeprazole
- •Inform Your Physician Before Taking This Drug If
- •If any of the following develop, consult your physician promptly for guidance.
- •Inform Your Physician Before Taking This Drug If
- •Ibuprofen
- •Inform Your Physician Before Taking This Drug If
- •Minocycline
- •Inform Your Physician Before Taking This Drug If
- •If any of the following develop, consult your physician promptly for guidance.
- •Indomethacin
- •Inform Your Physician Before Taking This Drug If
- •Betaxolol
- •Inform Your Physician Before Taking This Drug If
- •Erythromycin
- •Inform Your Physician Before Taking This Drug If
- •If any of the following develop, consult your physician promptly for guidance.
- •Loperamide
- •Inform Your Physician Before Taking This Drug If
- •Phenobarbital
- •Inform Your Physician Before Taking This Drug If
Omeprazole
(oh ME pra zohl)
Introduced: 1986
Prescription: USA: Yes Canada: Yes
Available as Generic: USA: No Canada: No
Brand Name: Prilosec (formerly Losec)
Class: Antiulcer, gastric acid inhibitor
Controlled Drug: USA: No
Canada: No
Principal Uses
As a Single Drug Product: Used primarily to inhibit the secretion of stomach acid, an important first step in the treatment of several conditions associated with excessive stomach acid production: acute and chronic gastritis, reflux esophagitis, Zollinger-Ellison syndrome, mastocytosis, endocrine adenomas, active gastric and duodenal ulcer.
How This Drug Works: By inhibiting the action of a specific enzyme system in the acid-secreting cells of the stomach lining, this drug arrests the production of stomach acid and thereby (1) eliminates a principal cause of the condition under treatment, and (2) creates an environment conducive to healing.
Available Dosage Forms and Strengths
Capsules, delayed-release — 20 mg
Usual Adult Dosage Range: Reflux esophagitis: 20 mg to 40 mg once daily
for 4 to 8 weeks.
Excessive stomach acid conditions: 60 mg once daily for as long as necessary.
Gastric and duodenal ulcer: 20 mg to 40 mg once daily for 4 to 8 weeks.
In extreme conditions, doses of 120 mg daily, in divided doses, have been used. Note: Actual dosage and administration schedule must be determined by the physician for each patient individually.
Dosing Instructions: Take immediately before eating, preferably the morning meal. The capsule should be swallowed whole without opening; the contents should not be crushed or chewed. This drug may be taken concurrently with antacids if they are needed to relieve stomach pain.
Usual Duration of Use:
Continual use on a regular schedule for 2 to 3 weeks is usually necessary to determine this drug's effectiveness in suppressing stomach acid production. Long-term use (months to years) requires periodic evaluation of response and dosage adjustment. Consult your physician on a regular basis.
Possible Advantages of This Drug
Effectively inhibits acid secretion at all times: basal conditions (stomach empty and at rest) and following food, alcohol, smoking or other stimulants.
Is more effective than H-2 receptor blocking drugs in treating severe reflux esophagitis and refractory duodenal ulcer.
Currently a "Drug of Choice"
for the short-term treatment of severe reflux esophagitis and for the long-term treatment of Zollinger-EUison syndrome.
This Drug Should Not Be Taken If
you have had an allergic reaction to it previously.
you have a currently active bone marrow or blood cell disorder.
Inform Your Physician Before Taking This Drug If
you have a history of liver disease or impaired liver function.
you have a history of any type of bone marrow or blood cell disorder, especially one that is drug-induced.
you are currently taking any anticoagulant medication, diazepam (Valium) or phenytoin (Dilantin, etc.).
Possible Side-Effects
(natural, expected and unavoidable drug actions) None reported.
Possible Adverse Effects
(unusual, unexpected and infrequent reactions)