Sehu - Ophthalmic Pathology-2005

OPHTHALMIC PATHOLOGY

An illustrated guide for clinicians

K.WENG SEHU AND WILLIAM R. LEE

Ophthalmic

Pathology

An illustrated guide for clinicians

Ophthalmic Pathology

An illustrated guide for clinicians

K Weng Sehu

Tennent Institute of Ophthalmology, University of Glasgow, UK

William R Lee

Tennent Institute of Ophthalmology, University of Glasgow, UK

© 2005 K.W. Sehu and W. R. Weng Published by Blackwell Publishing Ltd

BMJ Books is an imprint of the BMJ Publishing Group Limited, used under licence

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All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by the UK Copyright, Designs and Patents Act 1988, without the prior permission of the publisher.

First published in 2005

Library of Congress Cataloging-in-Publication Data

Sehu, K. Weng

Ophthalmic pathology: an illustrated guide for clinicians/K. Weng Sehu, William R. Lee

p.;	cm.
includes index.
ISBN-13: 978 0 727917 79		9 (alk. paper)
ISBN-10: 0 727917 79 X (alk. paper)
1. Eye—Disease—Atlases		2. Eye—Diseases.

[DNLM: 1. Eye Diseases—pathology—Atlases.] I. Lee, William R., 1932– II. Title. RE71.S44 2005

617.7—dc22

2005001742

A catalogue record for this title is available from the British Library

ISBN-13: 978 0 727917 79 9

ISBN-10: 0 727917 79 X

Set in Chennai, India by Newgen Imaging Systems (P) Ltd

Printed and bound in Haryana, India by Replika Press PVT Ltd.

Commissioning Editor: Mary Banks

Development Editor: Veronica Pock

Production Controller: Debbie Wyer

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http://www.blackwellpublishing.com

The publisher’s policy is to use permanent paper from mills that operate a sustainable forestry policy, and which has been manufactured from pulp processed using acid-free and elementary chlorine-free practices. Furthermore, the publisher ensures that the text paper and cover board used have met acceptable environmental accreditation standards.

v

Contents

Preface, vii

Acknowledgements, ix

1Basics, 1

2Eyelid and lacrimal sac, 17

3Conjunctiva, 39

4Cornea, 61

5Orbit and optic nerve, 93

6Development and malformation, 121

7Glaucoma, 135

8Inflammation, 157

9Wound healing and trauma, 183

10Retina: vascular diseases, degenerations, and dystrophies, 203

11Intraocular tumours, 243

Index, 269

vii

Preface

Our original purpose in writing this book was to make available illustrations of the common pathological entities encountered in routine practice for junior colleagues who are undertaking postgraduate training. In so doing, we have attempted to provide an understanding of the basic processes involved in ophthalmic disease and thus this book should also be of interest to qualified ophthalmologists. Computer technology has advanced to such a level that it has enabled us to derive and modify images collected over a period of 40 years. A CD ROM has been created as it provides the highest quality annotated illustrations that are easily accessible with the additional facility to remove the annotations for self-testing. The electronic images allow viewing of screen illustrations at much higher magnifications than would be possible in a printed textbook. An illustrated text has also been prepared for portable convenience. Basic clinical and management sections have been added into each chapter to provide relevant background to the pathology presented. As a result, we hope that this book will also be of value to those pathologists with an interest in ophthalmic pathology by helping to bridge the gap between laboratory and clinical practice.

Weng Sehu

William Lee

ix

Acknowledgements

It is our pleasure to acknowledge the help and advice we have received from Dr Fiona Roberts, Dr Ridia Lim, Professor Peter McCluskey, and Dr Harald Schilling.

Dedication

To our respective families.