Tranquilizers and Sedative Drugs

1. The patient has taken the mixture prescribed by neuropathologist for neurasthenia for 2 weeks. Patient felt better but developed coryza, conjunctivitis, rash, inertia, decrease of memory. Bromizm was diagnosed. What should be prescribed to decrease symptoms?

*A. Sodium chloride

B. Asparcam

C. Glucose solution 5%

D. Polyglucin

E. Diazepam

2. A patient who has been treated with diazepam on account of neurosis complains of toothache. Doctor administered him an analgesic, but its dose was lower than average therapeutic dose. What phenomenon did the doctor take into account while prescribing the patient an underdose?

*A. Potentiation

B. Cumulation

C. Tolerance

D. Summation

E. Drug dependence

3. A 42-year-old man who has been injured in a car accident is brought into the emergency room. His blood alcohol level on admission is 250 mg/dL. Hospital records show a prior hospitalization for alcohol related seizures. His wife confirms that he has been drinking heavily for 3 weeks. What treatment should be provided to the patient if he goes into withdrawal?

*A. Diazepam

B. Pentobarbital

C. None

D. Phenobarbital

E. Phenitoin

4. A student asked doctor to help him to overcome the fear of stomatological manipulations. What drug has the doctor advised to take?

*A. Diazepamum

B. Aminazinum

C. Droperidolum

D. Dimedrolum

E. Pyracetamum

5. A woman, who leads an active way of life, has appealed to a polyclinic with complains of bad mood, migraine, emotional lability, heart pain. What drug for neurosis treatment should be prescribed, taking into consideration that the patient spends a lot of time at work?

*A. Gidazepamum

B. Aminazinum

C. Phenazepamum

D. Triphthazinum

E. Phenobarbitalum

6. To perform an oral surgery a dentist prescribed a combination of drugs with the purpose of analgesia. What tranquilizer – derivative of benzodiazepine – is used for this purpose?

*A. Diazepamum

B. Droperidolum

C. Trioxazinum

D. Sulpiridum

E. Aminazinum

7. A patient suffers from repeating attacks of epileptic convulsions with loss of consciousness. What group of drug is used first of all for seizures elimination in this case?

*A. Tranquilizers

B. Neuroleptics

C. Miorelaxants

D. Analeptics

E. Sedative drugs

8. After the psychical trauma, the patient began to complain of alarm, anxiety, and pavor. What derivative of benzodiazepine may be prescribed to patient?

*A. Nitrazepam

B. Analginum

C. Bisacodyl

D. Metoclopramide

E. Heparin

9. A 45-year-old patient suffers from neurosis characterized by irritability, sleeplessness, motiveless anxiety. What drug would eliminate all the symptoms?

*A. Diazepam

B. Pyracetam

C. Levodopa

D. Caffeine sodium benzoate

E. Ethosuximide

Psychostimulants, Nootropics, and Analeptics

1. Analeptical remedy of reflective type from the H-cholinomimetics group was given to the patient for restoration of breathing after poisoning with carbon monooxide. What medicine was prescribed to the patient?

*A. Lobeline hydrochloride

B. Mesaton

C. Adrenaline gydrochloride

D. Pentamin

E. Atropine sulphate

2. An aged patient complains of headache, dizziness, quick tiredness, worsening of memory. Anamnesis: craniocerebral injury. Medicine of what group should be prescribed?

*A. Nootropics

B. Sedatives

C. Analgesics

D. Hypnotics

E. Neuroleptics

3. The CNS stimulation produced by methylxanthines, such as caffeine, is most likely due to the antagonism of one of the following receptors:

*A. Adenosine receptors

B. Cholinergic muscarinic receptors

C. Glycine receptors

D. Glutamate receptors

E. GABA receptors

4. A patient with respiratory depression has been delivered to a hospital. What is the pharmacological group drugs that can stimulate breathing?

*A. Analeptics

B. Tranquilizers

C. Neuroleptics

D. Antidepressants

E. Analgesics

5. Parents have appealed to a neurologist with complaints of the disorder of mental work, reduction of learning abilities of their 9-year-old child. Decrease of mentality, memory, intellectual work capacity was detected. The prescription of what group of psychotropic drugs is needed in this case?

*A. Nootropic agents

B. Antidepressants

C. Tranquilizers

D. Neuroleptics

E. Adaptogenes

6. An elderly man complains of headache, dizziness, rapid fatigability, memory impairment. In the anamnesis there is craniocerebral trauma. What group of drugs is needed to be prescribed?

*A. Nootropic agents

B. Soporific

C. Neuroleptics

D. Analgetics

E. Tranquilizers

7. It is necessary to prescribe a patient a drug, which improves memory and mental work in case of organic damages of the brain. What drug should be prescribed?

*A. Pyracetamum

B. Nitrazepamum

C. Mezapamum

D. Diazepamum

E. Coffeinum-natrii benzoas

8. A newborn child has asphyxia. What drug is it necessary to prescribe for the stimulation of breathing of the newborn?

*A. Aethimizolum

B. Lobelini hydrochloridum

C. Prazosinum

D. Atropini sulfas

E. Proserinum

9. During a tooth extraction a patient lost consciousness. What drug is it necessary to prescribe to bring the patient out of this condition quickly?

*A. Coffeinum-natrii benzoas

B. Amitriptylinum

C. Analginum

D. Novocainum

E. Papaverini hydrochloridum

10. A 36-year-old male patient has a cardiocerebral trauma accompanied by weak breathing, thread pulse, reflexes are absent. What is the most expedient way of pyracetame introduction in this case?

*A. Intravenous

B. Rectal

C. Subcutaneous

D. Peroral

E. Inhalation

11. A patient with complaints of memory impairment and intellectual work capacity decrease after a head trauma is hospitalized into a neurology department. What medicine can be recommended to improve brain tissues metabolism?

*A. Pyracetamum

B. Meridilum

C. Sydnocarbum

D. Coffeinum-natrii benzoas

E. Analginum

DRUGS WHICH INFLUENCE FUNCTIONS

OF INTERNAL ORGANS

Drugs Affecting Respiratory

System

1. Spasm of smooth muscle of bronchi developed in the patient. Usage of activators of what membrane cytoreceptors is physiologically valid to decrease attack?

*A. -Adrenoreceptors

B. - and -adrenoreceptors

C. M-Cholinoreceptors

D. H-Cholinorceptors

E. -Adrenoreceptors

2. A 13-year-old girl with history of asthma complained of cough, dyspnea, and wheezing. Her symptoms became so severe that her parents brought her to the emergency room. Physical examination revealed diaphoresis, dyspnea, tachycardia, and tachypnea. Her respiratory rate was 42/min, pulse rate was 110 beats per minute, and blood pressure was 130/70 mm Hg. Choose from the following list the most appropriate drug to reverse the bronchoconstriction rapidly:

*A. Salbutamol

B. Ipratropium

C. Methylprednisolone

D. Beclomethasone

E. Cromolin sodium

3. A 45-year-old woman suffers from allergic seasonal coryza caused by the ambrosia blossoming. What drug from the stabilizer of the adipose cells group can be used for prevention of this disease?

*A. Ketotifen

B. Tavegyl

C. Diazoline

D. Phencarol

E. Dimedrol

4. Which one of the following β-adrenoceptor agonists has such a slow onset of action that it is not indicated for the relief of acute asthma symptoms?

*A. Salmeterol

B. Albuterol

(C) Epinephrine

(D) Terbutaline

(E) Isoproterenol

5. The patient with bronchial asthma was treated by euphyllinum, after that the condition of patient was improved. What mechanism of action has this drug?

*A. Blockade of phosphodiesterase

B. Activation of adenylcyclase

C. Activation of Na,K-ATPase

D. Blockade of M-cholinoreceptors

E. Prevention of discharge of histamine from basophiles

6. A 12-year-old girl with a childhood history of asthma complained of cough, dyspnea, and wheezing after visiting a riding stable. Her symptoms became so severe that her parent brought her to the emergency room. Physical examination revealed diaphoresis, dyspnea, tachycardia, and tachypnea. Her respiratory rate was 42/min, pulse rate was 110 beats per minute, and blood pressure was 132/65 mm Hg. What drug is contraindicated in this patient?

*A. Intravenous propranolol

B. Inhaled beclomethasone

C. Inhaled ipratropium

D. Inhaled albuterol

E. Inhaled cromolin sodium

7. A 12-year-old girl with a childhood history of asthma complained of cough, dyspnea, and wheezing after visiting a riding stable. Her symptoms became so severe that her parent brought her to the emergency room. Physical examination revealed diaphoresis, dyspnea, tachycardia, and tachypnea. Her respiratory rate was 42/min, pulse rate was 110 beats per minute, and blood pressure was 132/65 mm Hg. The most appropriate drug to rapidly reverse bronchoconstriction is:

*A. Inhaled albuterol

B. Inhaled beclomethasone

C. Inhaled ipratropium

D. Inhaled cromolin sodium

E. Intravenous propranolol

8. A 12-year-old girl with a childhood history of asthma complained of cough, dyspnea, and wheezing after visiting a riding stable. Her symptoms became so severe that her parent brought her to the emergency room. Physical examination revealed diaphoresis, dyspnea, tachycardia, and tachypnea. Her respiratory rate was 42/min, pulse rate was 110 beats per minute, and blood pressure was 132/65 mm Hg. Indicate the drug, which likely to be ineffective in this patient.

*A. Inhaled cromolin sodium

B. Inhaled beclomethasone

C. Inhaled ipratropium

D. Inhaled albuterol

E. Intravenously prednisolone

9. The ethyl alcohol was been introduced to patient with acute pulmonary edema. What action of ethyl alcohol was been used in this case?

*A. Ethyl alcohol decreases the superficial tension of foam and transforms it to the fluid

B. Hypnotic action

C. Analgesic action

D. Ethyl alcohol increase the rate of metabolism into the body

E. Ethyl alcohol decreases the permeability of lung’s vessels

10. A patient with bronchial asthma attack has a concomitant disease – angina pectoris. What bronchodilator should be prescribed in this case?

*A. Salbutamolum

B. Adrenaline

C. Isadrinum

D. Atropini sulfas

E. Noradrenalini hydrotartras

11. Chronic bronchitis is diagnosed. The patient is treated with a mucolytic – a drug, which stimulates formation of surfactant, improves rheological properties of sputum, reduces its viscosity. What is this drug?

*A. Ambroxolum

B. Papaverini hydrochloridum

C. Libexinum

D. Codeine

E. Panadolum

12. The bronchospasm has developed in patient using -adrenoblockers during long time. Choose the most rational drug group for interruption of bronchospasm in this patient.

*A. Miotropic spasmolytics

B. -adrenomimetics

C. Adrenomimetics with indirect action

D. M-cholinomimetics

E. Cholinesterase inhibitors

13. The patient with asthmatic status is delivered to urgent unit. The patient is suffering from bronchial asthma during 12 years. Earlier attacks were reduced by salbutamol but now this drug is ineffective. What drug should be administered to patient first of all?

*A. Prednisolon

B. Acyclovir

C. Oxytocin

D. Famotidine

E. Bisacodyl

14. The patient with purulent bronchitis is delivered to the pulmonary department. For depression of a sputum and simplification of its release the doctor prescribes to him the drug A. Indicate this drug.

*A. Acetylcysteine

B. Tincture Valerianae

C. Cholosasum

D. Prednisolon

E. Morphine

15. Patient with acute laryngotracheitis suffers from dry cough. Prescribe antitussive drug for this patient.

*A. Glaucine

B. Ambroxol

C. Acetylcysteine

D. Mucaltinum

E. Morphine

16. A patient suffering from chronic bronchitis takes a synthetic mucolytic drug that facilitates the sputum thinning. What drug is it?

*A. Acetylcysteine

B. Enalapril

C. Heparin

D. Diazepam

E. Furosemide