Drugs influencing peripheral nervous system Drugs Affecting the Afferent Innervation

1. The patient had received the trauma of eye due to the hits of the metal shaving. Patient has oedema of eye, significant hyperaemia, and acute pain. The removal of an alien body is possible only with local anaesthesia. Choose the drug for local anaesthesia in this case.

*A. Dicainum (tetracaine).

B. Cocaine.

C. Novocainum (procaine).

D. Trimecaine.

E. Anaesthesinum (benzocaine).

2. An unconscious patient was delivered to the hospital. The doctor has given him to smell the ammonia solution to restore him to consciousness. What is the type of action, which provides the pharmacological effect of this drug?

*A. Reflex action.

B. Resorptive action.

C. Local action.

D. Selective action.

E. Etiotropic action.

3. The conduction anaesthesia was given to patient before tooth extraction. In several minutes after this the oedema and hyperaemia had developed around injection site; the general weakness and hypotension had developed in patient. Determine the described complication.

*A. Allergic reaction.

B. Tolerance.

C. Tachyphylaxis.

D. Drug dependence.

E. Idiosyncrasy.

4. These drugs cause the coagulation of mucous proteins, condense the superficial surface of mucous membranes, and display anti-inflammatory action. What is this group of drugs?

*A. Astringent drugs.

B. Local anaesthetics.

C. Irritative drugs.

D. Covering drugs.

E. Adsorbing drugs.

5. This drug has low solubility in water; therefore it is used for terminal anaesthesia in ointments, pastas, powders, candles. Also it is prescribed in powders for internal use in stomach pain and vomiting. Indicate this drug.

*A. Anaesthesinum (benzocaine).

B. Novocainum (procaine).

C. Dicainum (tetracaine).

D. Trimecaine.

E. Lidocaine.

6. A patient has heart pain for some time, which is not connected to physical loading. Call the irritative substance which narrows the vessels of mucous in local use, and causes reflex expansion of coronary vessels.

*A. Menthol.

B. Ammonia solution.

C. Turpentine oil.

D. Camphor.

E. Sinapisms.

7. Combine operator had received the eye trauma during crop harvest. What local anaesthetic should be used for removal of foreign body from eye?

*A. Dicainum (tetracaine).

B. Novocainum (procaine).

C. Lidocaine.

D. Trimecaine.

E. Sovcainum.

8. A doctor made the sensitivity test to novocainum in patient before the infiltration anaesthesia. The test is positive. What drug should be used for infiltration anaesthesia to this patient?

*A. Lidocaine.

B. Novocainamide.

C. Dicainum.

D. Anaesthesinum.

E. Cocainum.

9. A patient with abscess of shoulder was delivered to the surgery department. During examination a doctor has found out ventricular extrasystoles. What type of anaesthesia is most expedient in this patient?

*A. Local anaesthesia with lidocaine.

B. Spinal anaesthesia with sovcainum.

C. General anaesthesia with hexenalum.

D. General anaesthesia with ether pro narcosis.

E. General anaesthesia with ketamine.

10. A patient with acute attack of appendicitis was delivered to surgery unit. An anaesthesiologist suggested local anaesthesia for operation. But during examination it became clear that the patient has the frequent allergic reaction upon the drugs. Choose the drug which can be used for local anaesthesia in this case.

*A. Lidocaine.

B. Anaesthesinum.

C. Dicainum.

D. Cocaine.

E. Novocainum.

11. The terminal anaesthesia develops in the result of drug’s influence upon the following element of skin and mucous membranes:

*A. Sensitive nervous ending.

B. Epidermis.

C. Hypodermic fatty tissue.

D. Capillaries wall.

E. Derma.

12. A patient needs performing of paranefral Vishnevsky’s blockade. What concentration of novocainum solution is used in this case?

*A. 0.125–0.5%.

B. 0.5–1%.

C. 1–2%.

D. 2–4%.

E. 4–5%.

13. A patient with high sensitivity to sulfonamides had appealed to the ophthalmic department with trauma of eye. What drug should be used for anaesthesia of conjunctiva in this case?

*A. Lidocaine.

B. Novocainum.

C. Trimecaine.

D. Dicainum.

E. Anaesthesinum.

14. Call the drug from group of local anaesthetics which is not desirable to prescribe simultaneously with sulfonamides.

*A. Novocainum.

B. Anaesthesinum.

C. Lidocaine.

D. Trimecaine.

E. Ultracaine.

15. A doctor has prescribed an ointment “Efcamonum” to patient. This ointment is irritative drug according to mechanism of action. Indicate the case, in which “Efcamonum” is contraindicated.

*A. Skin injury.

B. Neuralgia.

C. Pain in a joint.

D. Myalgia.

E. Neuritis.

16. The action of novocainum is decreased in areas of inflammation because the disturbance of hydrolysis of novocainum salt and releasing of active basic substance develop. What is the cause of this phenomenon?

*A. Local tissue acidosis.

B. Local tissue alkalosis.

C. Inhibition of carboanhydrase.

D. Activation of succinate dehydrogenase.

E. Inhibition of oxidative phosphorylation.

17. A third year student during the practice should put the sinapisms on the back of patient. For this purpose he has moistened the sinapisms with very hot water (the temperature is more than 60⁰ C). In 30 minutes the student has found out that the skin of patient has not reddened in place of applied sinapisms. What is the cause of this phenomenon?

*A. Hot water causes inactivation of mirosine.

B. Hot water causes inactivation of cholinesterase.

C. Hot water causes activation of mirosine.

D. Hot water causes inactivation of MAO.

E. Hot water causes activation of MAO.

18. A 25-year-old woman with red and itchy eczematoid dermatitis visits your office. She had a dental procedure one day earlier with administration of local anaesthetic. There were no other findings, although she indicated that she had a history of allergic reactions. Which of the following drugs is most likely involved?

*A. Procaine.

B. Bupivacaine.

C. Lidocaine.

D. Etidocaine.

E. Cocaine.

19. A patient with an abscess was admitted to a surgical department for operative treatment. During additional examination ventricular premature beats were detected. What drug is the most expedient for anaesthesia in this case?

*A. Lidocainum.

B. Phthorothanum.

C. Hexenalum.

D. Aether pro narcosi.

E. Ketaminum.