- •Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation
- •Dedication
- •Preface
- •Reader Background
- •Rationale
- •Description of the Chapters
- •Features
- •The Author
- •Table of Contents
- •1.1 Introduction
- •1.2 Sources of Endogenous Bioelectric Signals
- •1.3 Nerve Action Potentials
- •1.4 Muscle Action Potentials
- •1.4.1 Introduction
- •1.4.2 The Origin of EMGs
- •1.5 The Electrocardiogram
- •1.5.1 Introduction
- •1.6 Other Biopotentials
- •1.6.1 Introduction
- •1.6.2 EEGs
- •1.6.3 Other Body Surface Potentials
- •1.7 Discussion
- •1.8 Electrical Properties of Bioelectrodes
- •1.9 Exogenous Bioelectric Signals
- •1.10 Chapter Summary
- •2.1 Introduction
- •2.2.1 Introduction
- •2.2.4 Schottky Diodes
- •2.3.1 Introduction
- •2.4.1 Introduction
- •2.5.1 Introduction
- •2.5.5 Broadbanding Strategies
- •2.6 Photons, Photodiodes, Photoconductors, LEDs, and Laser Diodes
- •2.6.1 Introduction
- •2.6.2 PIN Photodiodes
- •2.6.3 Avalanche Photodiodes
- •2.6.4 Signal Conditioning Circuits for Photodiodes
- •2.6.5 Photoconductors
- •2.6.6 LEDs
- •2.6.7 Laser Diodes
- •2.7 Chapter Summary
- •Home Problems
- •3.1 Introduction
- •3.2 DA Circuit Architecture
- •3.4 CM and DM Gain of Simple DA Stages at High Frequencies
- •3.4.1 Introduction
- •3.5 Input Resistance of Simple Transistor DAs
- •3.7 How Op Amps Can Be Used To Make DAs for Medical Applications
- •3.7.1 Introduction
- •3.8 Chapter Summary
- •Home Problems
- •4.1 Introduction
- •4.3 Some Effects of Negative Voltage Feedback
- •4.3.1 Reduction of Output Resistance
- •4.3.2 Reduction of Total Harmonic Distortion
- •4.3.4 Decrease in Gain Sensitivity
- •4.4 Effects of Negative Current Feedback
- •4.5 Positive Voltage Feedback
- •4.5.1 Introduction
- •4.6 Chapter Summary
- •Home Problems
- •5.1 Introduction
- •5.2.1 Introduction
- •5.2.2 Bode Plots
- •5.5.1 Introduction
- •5.5.3 The Wien Bridge Oscillator
- •5.6 Chapter Summary
- •Home Problems
- •6.1 Ideal Op Amps
- •6.1.1 Introduction
- •6.1.2 Properties of Ideal OP Amps
- •6.1.3 Some Examples of OP Amp Circuits Analyzed Using IOAs
- •6.2 Practical Op Amps
- •6.2.1 Introduction
- •6.2.2 Functional Categories of Real Op Amps
- •6.3.1 The GBWP of an Inverting Summer
- •6.4.3 Limitations of CFOAs
- •6.5 Voltage Comparators
- •6.5.1 Introduction
- •6.5.2. Applications of Voltage Comparators
- •6.5.3 Discussion
- •6.6 Some Applications of Op Amps in Biomedicine
- •6.6.1 Introduction
- •6.6.2 Analog Integrators and Differentiators
- •6.7 Chapter Summary
- •Home Problems
- •7.1 Introduction
- •7.2 Types of Analog Active Filters
- •7.2.1 Introduction
- •7.2.3 Biquad Active Filters
- •7.2.4 Generalized Impedance Converter AFs
- •7.3 Electronically Tunable AFs
- •7.3.1 Introduction
- •7.3.3 Use of Digitally Controlled Potentiometers To Tune a Sallen and Key LPF
- •7.5 Chapter Summary
- •7.5.1 Active Filters
- •7.5.2 Choice of AF Components
- •Home Problems
- •8.1 Introduction
- •8.2 Instrumentation Amps
- •8.3 Medical Isolation Amps
- •8.3.1 Introduction
- •8.3.3 A Prototype Magnetic IsoA
- •8.4.1 Introduction
- •8.6 Chapter Summary
- •9.1 Introduction
- •9.2 Descriptors of Random Noise in Biomedical Measurement Systems
- •9.2.1 Introduction
- •9.2.2 The Probability Density Function
- •9.2.3 The Power Density Spectrum
- •9.2.4 Sources of Random Noise in Signal Conditioning Systems
- •9.2.4.1 Noise from Resistors
- •9.2.4.3 Noise in JFETs
- •9.2.4.4 Noise in BJTs
- •9.3 Propagation of Noise through LTI Filters
- •9.4.2 Spot Noise Factor and Figure
- •9.5.1 Introduction
- •9.6.1 Introduction
- •9.7 Effect of Feedback on Noise
- •9.7.1 Introduction
- •9.8.1 Introduction
- •9.8.2 Calculation of the Minimum Resolvable AC Input Voltage to a Noisy Op Amp
- •9.8.5.1 Introduction
- •9.8.5.2 Bridge Sensitivity Calculations
- •9.8.7.1 Introduction
- •9.8.7.2 Analysis of SNR Improvement by Averaging
- •9.8.7.3 Discussion
- •9.10.1 Introduction
- •9.11 Chapter Summary
- •Home Problems
- •10.1 Introduction
- •10.2 Aliasing and the Sampling Theorem
- •10.2.1 Introduction
- •10.2.2 The Sampling Theorem
- •10.3 Digital-to-Analog Converters (DACs)
- •10.3.1 Introduction
- •10.3.2 DAC Designs
- •10.3.3 Static and Dynamic Characteristics of DACs
- •10.4 Hold Circuits
- •10.5 Analog-to-Digital Converters (ADCs)
- •10.5.1 Introduction
- •10.5.2 The Tracking (Servo) ADC
- •10.5.3 The Successive Approximation ADC
- •10.5.4 Integrating Converters
- •10.5.5 Flash Converters
- •10.6 Quantization Noise
- •10.7 Chapter Summary
- •Home Problems
- •11.1 Introduction
- •11.2 Modulation of a Sinusoidal Carrier Viewed in the Frequency Domain
- •11.3 Implementation of AM
- •11.3.1 Introduction
- •11.3.2 Some Amplitude Modulation Circuits
- •11.4 Generation of Phase and Frequency Modulation
- •11.4.1 Introduction
- •11.4.3 Integral Pulse Frequency Modulation as a Means of Frequency Modulation
- •11.5 Demodulation of Modulated Sinusoidal Carriers
- •11.5.1 Introduction
- •11.5.2 Detection of AM
- •11.5.3 Detection of FM Signals
- •11.5.4 Demodulation of DSBSCM Signals
- •11.6 Modulation and Demodulation of Digital Carriers
- •11.6.1 Introduction
- •11.6.2 Delta Modulation
- •11.7 Chapter Summary
- •Home Problems
- •12.1 Introduction
- •12.2.1 Introduction
- •12.2.2 The Analog Multiplier/LPF PSR
- •12.2.3 The Switched Op Amp PSR
- •12.2.4 The Chopper PSR
- •12.2.5 The Balanced Diode Bridge PSR
- •12.3 Phase Detectors
- •12.3.1 Introduction
- •12.3.2 The Analog Multiplier Phase Detector
- •12.3.3 Digital Phase Detectors
- •12.4 Voltage and Current-Controlled Oscillators
- •12.4.1 Introduction
- •12.4.2 An Analog VCO
- •12.4.3 Switched Integrating Capacitor VCOs
- •12.4.6 Summary
- •12.5 Phase-Locked Loops
- •12.5.1 Introduction
- •12.5.2 PLL Components
- •12.5.3 PLL Applications in Biomedicine
- •12.5.4 Discussion
- •12.6 True RMS Converters
- •12.6.1 Introduction
- •12.6.2 True RMS Circuits
- •12.7 IC Thermometers
- •12.7.1 Introduction
- •12.7.2 IC Temperature Transducers
- •12.8 Instrumentation Systems
- •12.8.1 Introduction
- •12.8.5 Respiratory Acoustic Impedance Measurement System
- •12.9 Chapter Summary
- •References
Modulation and Demodulation of Biomedical Signals |
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FIGURE 11.18
(A) Circuit for an adaptive delta modulator. (B) Demodulator for ADM. A long time-constant LPF is generally used instead of an ideal integrator for filtering vm.
11.7 Chapter Summary
Broadly speaking, modulation is a process in which a low-frequency modulating signal acts on a high-frequency carrier wave in some way so that the high-frequency modulated carrier can be transmitted (e.g., as radio waves, ultrasound waves, light waves, etc.) to a suitable receiver; after this the process of demodulation occurs, recovering the modulating signal. In the
© 2004 by CRC Press LLC
462 |
Analysis and Application of Analog Electronic Circuits |
frequency domain, the low-frequency power spectrum of the signal is translated upward in frequency to lie around the carrier frequency. A major purpose of modulation is to permit long-range transmission of the modulating signal by a relatively noise-free modality.
Why transmit modulated carriers? After all, traditional short-distance telephony transmits audio information directly on telephone lines. The answer lies in the signal spectrum. The low frequencies associated with many endogenous physiological signals cannot be transmitted by conventional voice telephony; modulation must be used. The carrier modality can be radio waves, ultrasound, or light on fiber optic cables. For example, when the modulating signal is an ECG, its power spectrum is too low for direct transmission by telephone lines. However, the ECG can narrow-band fre- quency-modulate (NBFM) an audio-frequency carrier that can be transmitted on phone lines and demodulated at the receiver. In a case in which an ambulance is en route carrying a patient, the ECG can directly NBFM an RF carrier, which is received and demodulated at the hospital’s ER.
Subcarrier modulation can be used as well. Here several low-frequency physiological signals such as ECG, blood pressure, and respiration can NBFM an audio subcarrier, each with a different frequency. The modulated subcarriers are added together and used to modulate amplitude of frequency of an RF carrier, which is transmitted. Subcarrier FM can also be used with ultrasonic “tags” to monitor marine animals such as whales and dolphins. The tag is attached to the animal and reports such parameters as depth, water temperature, heart rate, etc. The subcarriers are separated following detection at the receiver by band-pass filters and then demodulated.
The section about AM examined the process in the frequency domain and gave examples of selected circuits used in AM and single-sideband AM. Double-sideband, suppressed-carrier AM was shown to be the simple result of multiplying the carrier by the modulating signal. Examples of DSBSCM were shown to include Wheatstone bridge outputs given ac carrier excitation and the output of an LVDT. Broadband and narrowband FM were examined theoretically; circuits and systems used to generate NBFM, such as the phaselocked loop (PLL), were described as well. Integraland relaxation-pulse frequency modulation were introduced.
The section on demodulation illustrated circuits and systems used to demodulate AM, DSBSCM, FM, and NBFM signals. Again, the PLL was shown to be effective at demodulation. Modulation of digital (e.g., TTL, ECL) carriers includes FM and – (sigma–delta) modulation, pulse-width or duty-cycle modulation, and adaptive delta modulation. Means of demodulating digital modulated signals were described.
Home Problems
11.1An analog pulse instantaneous pulse frequency demodulator (IPFD) must generate a hyperbolic (not exponential) capacitor discharge waveform in order to convert interpulse intervals to elements of instantaneous frequency
© 2004 by CRC Press LLC
Modulation and Demodulation of Biomedical Signals |
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FIGURE P11.1
(IF). IF is defined as the reciprocal of the interval between two adjacent impulses in a sequence of pulses. When the (k + 1)th pulse in a sequence occurs, the kth hyperbolic waveform voltage is sampled and held, generating the kth element of IF, which is held until the (k + 2)th pulse occurs, etc. The capacitor discharge will be a portion of a hyperbola for t ≥ 1 MS following the occurrence of each pulse. Mathematically, this can be stated:
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© 2004 by CRC Press LLC
464 |
Analysis and Application of Analog Electronic Circuits |
where Vcmax = 10 V; C = 1 μF; and τo = C/(βVcmax) = 0.001 sec. It can be shown that if the capacitor is allowed to discharge into a nonlinear conductance so that: inl (t) = β vc(t)2, the preceding hyperbolic vc(t) will occur (Northrop, 1997). Time t is measured from (tk + 0.001) sec (see the timing diagram below the schematic). This means that if tk+1 = (tk + 0.001), vc(0) = 10 V for an IF of 1000 pps. Note that prior to each discharge cycle, C is charged through the diode to +10 V.
In this problem, you are to analyze and design the active circuit of Figure P11.1 that causes inl (t) = βvc(t)2 and generates the hyperbolic vc(t) described. That is, find the numerical value of R required, given the preceding parameter values. Also find the numerical values for β and the peak inl (t).
11.2Show that the PLL circuit of Figure P11.2 generates FM. Show that the phase
output of the VCO is true wideband FM. (Hint: find the transfer function, θo /Xm.)
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FIGURE P11.2
11.3Make a Bode plot of θo /Xm for the system of Figure P11.3. Show the frequency range(s) at which FM is generated and phase modulation is generated.
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11.4The system illustrated in Figure P11.4 is an FM demodulator. The Km /s block represents the operation on the phase of the carrier by an ideal FM modulator.
© 2004 by CRC Press LLC
Modulation and Demodulation of Biomedical Signals |
465 |
Make a Bode plot of Vc/Xm and show the range of frequencies (of xm(t)) where ideal FM demodulation occurs (i.e., where Vc xm).
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FIGURE P11.4
11.5A quarter-square multiplier, shown in Figure P11.5, is used to demodulate a
double-sideband, suppressed-carrier modulated cosine wave. The modulated
wave is given by vm(t) = A xm(t) cos(ωc t). Write expressions for w, aw2, y, ay2, z and z, and show z xm(t). Assume that the LPF totally attenuates frequencies at and above ωc.
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FIGURE P11.5
11.6An analog multiplier (AM) followed by a low-pass filter (LPF) is used to demodulate a DSBSC signal, vm(t) = A xm(t) cos(ωc t), as shown in Figure P11.6. Give algebraic expressions for z and z. Assume that the LPF totally attenuates frequencies at and above ωc.
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© 2004 by CRC Press LLC