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APPENDIX FOUR Feline

Nonanestetized Cats

M-Mode Reference Ranges

X = mean, SD = standard deviation, d = diastole, s = systole, mm = millimeter, RV = right ventricle, RVW = right ventricular wall, LV = left ventricle, FS = fractional shortening, LVET = left ventricular ejection time, Vcf = velocity of circumferential fiber shortening, VS = ventricular septum, LVW = left ventricular wall, AO = aorta, LA = left atrium, EPSS = E point to septal separation, MAM = M- mode mitral annular septal wall motion, HR = heart rate, kg = kilogram, N = number.

Maine Coon Cats

M-Mode Reference Ranges

X = mean, SD = standard deviation, d = diastole, s = systole, mm = millimeter, RV = right ventricle, RVW = right ventricular wall, LV = left ventricle, FS = fractional shortening, VS = ventricular septum, LVW = left ventricular wall, AO = aorta, LA = left atrium, kg = kilogram, N = number.

Sedated or Anesthetized Cats

M-Mode Reference Ranges

X = mean, SD = standard deviation, d = diastole, s = systole, mm = millimeter, sec = second, circ = circumference, RV = right ventricle, LV = left ventricle, FS = fractional shortening, LVET = left ventricular ejection time, PEP = pre-ejection period, Vcf = velocity of circumferential fiber shortening, VS = ventricular septum, LVW = left ventricular wall, AO = aorta, LA = left atrium, HR = heart rate, kg = kilogram, N = number.

Growing Kittens

M-Mode Reference Ranges12

d = diastole, s = systole, mm = millimeter, LV = left ventricle, FS = fractional shortening, EF = ejection fraction, VS = ventricular septum, LVW = left ventricular wall, AO = aorta, LA = left atrium, HR = heart rate, kg = kilogram, N = number, = change.

Growing Kittens

M-Mode Regression Equations12

d = diastole, s = systole, cm = centimeter, LV = left ventricle, VS = ventricular septum, LVW = left ventricular wall, AO = aorta, LA = left atrium, N = number, BW = body weight in kg, Sxy = standard deviation from the regression line, HR = heart rate, Y = predicted value for parameter, x = body weight in kg.

Feline M-Mode Ratio Indices13

s = systole, d = diastole, VS = ventricular septum, LV = left ventricle, LVW = left ventricular wall, AO = aorta, LA = left atrium, LVOD = left ventricular outer diameter, WT = combined septal and wall thicknesses, wLV Area % = (LVd2 − LVs2)/ AOw2 , LVW area = myocardial wall area, FS = fractional shortening, FWT = WT/LVOD, A = change in short axis LV area, WA = myocardial short axis wall area, FWA = (LVOD2 − LVID2)/ LVOD2 = fractional change in short axis myocardial wall area, N = number, kg = kilogram.

w parameter = raw measurement / 1.043(W1/3), where W = kg.

a parameter = raw measurement / AO.

Feline

Two-Dimensional Measurement Reference Ranges

Leading edge method used. X = mean, SD = standard deviation, d = diastole, s = systole, mm = millimeter, cm = centimeter, LV = left ventricle, FS = fractional shortening, VS = ventricular septum, LVW = left ventricular wall, AO = aorta, LA = left atrium, PM = papillary muscle, HR = heart rate, kg = kilogram, N = number.

Feline

Spectral Doppler Reference Ranges

X = mean, SD = standard deviation, Vmax = peak velocity, m/sec = meters/second, AO = aorta, PA = pulmonary artery, MV E = mitral valve early diastolic flow, MV A = mitral valve late diastolic flow, acc = acceleration, dec = deceleration, dur = duration, IVRT = isovolumic relaxation time, PV S = pulmonary ventricular systolic flow, PV D = pulmonary vein diastolic flow, PV Ar = pulmonary vein atrial reverse flow, systolic fraction = % of systolic flow velocity integral compared to total cardiac cycle flow velocity integral, HR = heart rate, kg = kilogram, N = number.

PW Tissue Doppler

Left Ventricular References Ranges in Cats20

Em = early diastolic motion (same as E′), Am = late diastolic motion (same as A′), acc = acceleration, dec = deceleration, dur = duration, IVRT = isovolumic relaxation time, IVCT = isovolumic contraction time, N = number, kg = kilogram, HR = heart rate, X = mean, SD = standard deviation.

Color Tissue Doppler

Radial Left Ventricular Feline Reference Ranges6

LV = left ventricle, SA = short axis, cm = centimeter, sec = second, HR = heart rate, N =number, kg = kilogram, Sm = systolic myocardial velocity (same as S′), Em = early diastolic myocardial velocity (same as E′), Am = late diastolic myocardial velocity (same as A’), IVCT = isovolumic contraction time, IVRT = isovolumic relaxation time, DSH = domestic short hair, min = minimum, max = maximum.

Color Tissue Doppler

Longitudinal Left Ventricular Feline Reference Ranges6

Cm = centimeter, sec = second, HR = heart rate, N =number, kg = kilogram, Sm = systolic myocardial velocity (same as S′), Em = early diastolic myocardial velocity (same as E′), Am = late diastolic myocardial velocity (same as A′), IVCT = isovolumic contraction time, IVRT = isovolumic relaxation time, DSH = domestic short hair, SD = standard deviation, X = mean, min = minimum, max = maximum.

Color Tissue Doppler

Right Ventricular References Ranges in Cats21

RV Free Wall Tricuspid Annulus N

X ± SD

Right Ventricle

 

 

 

7.6

± 2.6

41

Em (cm/sec)

Am (cm/sec)

9.4

± 2.9

41

Em : Am

.85

± .29

41

Sm (cm/sec)

9.5

± 2.6

50

RVET (msec)

131 ± 26

50

Em dec rate (cm/sec2)

3.3 ± 1.3

50

IVRT (msec)

47 ± 13

50

IVCT (msec)

31 ± 13

50

MPI

.60 ± .16

50

HR

191 ± 31

 

Age

3 mo − 19 yr

 

kg

4.5 ± 1.7

 

Em = early diastolic velocity (same as E′), Am = late diastolic velocity (same as A′), Sm = systolic velocity (same as s′), dec rate = deceleration rate, IVRT = isovolumic relaxation time, IVCT = isovolumic contraction time, MPI = myocardial performance index, X = mean, SD = standard deviation, N = number, HR = heart rate, kg = kilogram, mo = month, yr = year.

References

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8.Drourr L, Lefbom BK, Rosenthal SL, et al. Measurement of M-mode echocardiographic parameters in healthy adult Maine Coon cats. Journal of the American Veterinary Medical Association

2005;226:734–737.

9.Chetboul V, Sampedrano CC, Tissier R, et al. Reference range values of regional left ventricular myocardial velocities and time intervals assessed by tissue Doppler imaging in young nonsedated Maine Coon cats. American Journal of Veterinary Research 2005;66:1936–1942.

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16.Abbott JA, MacLean HN. Two-dimensional echocardiographic assessment of the feline left atrium. J Vet Intern Med 2006;20:111–119.

17.Disatian S, Bright JM, Boon J. Association of age and heart rate with pulsed-wave Doppler measurements in healthy, nonsedated cats. J Vet Intern Med 2008;22:351–356.

18.Santilli RA, Bussadori C. Doppler echocardiographic study of left ventricular diastole in nonanaesthetized healthy cats. Vet J 1998;156:203–215.

19.Bright JM, Herrtage ME, Schneider JF. Pulsed Doppler assessment of left ventricular diastolic function in normal and cardiomyopathic cats. J Am Anim Hosp Assoc 1999;35:285–291.

20.Koffas H, Dukes-McEwan J, Corcoran M, et al. Pulsed tissue doppler imaging in normal cats and cats with hypertrophic cardiomyopathy. Journal of Veterinary Internal Medicine 2006;20:65–77.

21.Disatian S, Bright J, Boon J. The effects of age and heart rate on tricuspid annular motion velocities in healthy nonsedated cats. J Vet Int Med 2007;21:731–736.