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Cardiovascular Drugs

Cardiovascular drugs may be divided into three groups: drugs that affect the heart; drugs that affect blood pressure; and drugs that prevent blood clotting.

Drugs that affect the heart. Drugs may affect the heart in two major ways: changing the rate and forcefulness of the heartbeat.

The most common drugs used to change the rate and forcefulness of the heartbeat are the digitalis glycosides (cardiac glycosides). These drugs are used to treat patients in heart failure (when the heart is not contracting with sufficient force). Most of the digitalis glycosides are obtained from the leaf of the digitalis (foxglove) plant. The important effects of the digitalis glycosides are the strengthening of the myocardium (heart muscle) and the slowing of the rate of the heart contraction. Examples of digitalis are digoxin, and digitoxin.

Other drugs, which belong to the general class of sympathomimetics are used to increase heart rate and the force of contraction. These include isoproterenol and epinephrine.

Drugs used to correct abnormal heart rhythm are called antiarrhythmics. Examples of these drugs are quinidine, procainamide, lido-caine and propranolol.

IV. Language development.

1. Correct the following statements.

1. Digitalis glycosides are drugs which relax the muscles of vessel walls.

2 Digitalis glycosides can be made synthetically.

  1. Nitrites are used to prevent the formation of clots.

  2. Digitoxin is also used as a vasodilator.

  3. Heparin is administered only intravenously,

  4. Diuretics are used to increase blood pressure.

V. Speaking

l.Read the following dialogue and make your own using this vocabulary.

A Visit of a Pharmaceutical Firm Representative

Representative: Doctor, I would like to show you some pharmaceuticals. May I ask for a few minutes of your attention, please?

Doctor. Certainly. 1 have finished examining my patients and we can go upstairs to our office.

R.: It's very kind of you. Aren't I bothering you too much?

D.: Not at all. What hypotensive drugs do you have?

R.: We have normatencil which is used in the treatment of hypertension. The preparation regulates the figures of pressure and spares the kidney of a hypertonic patient preventing vascular complications and aggravation of the disease. Such a vascular kidney protection is a real advantage of the drug.

D.: Can it be used in ambulatory practice?

R:. To be sure! The ambulatory treatment is easily controlled as the preparation is not diuretic and does not contain reserpin.

D.: So, what are the doses and how is it used?

R.: 1-—2 tablets a day, 3 times a week or 20 days a month.

D:. And what about the contraindications?

R: They are the same as in all hypotensive drugs.

D.: Leave me the signature, 1 will read it and call you tomorrow. Thank you for coming and good bye.

R.: Bye.

Drugs that fight infection and drugs that prevent infectious diseases

  1. Active vocabulary.

antimicrobial

антибактеріальний препарат

sulfonamide

сульфаніламід

cholera

холера

smallpox

віспа

to expose (to)

виставляти, піддавати (чомусь)

tetanus

правець

diphtheria

дифтерія

poliomyelitis (polio)

поліомієліт, дитячий параліч

antiserum

антисироватка, імунна сироватка

globulin

глобулін